Our invention provides a device for and a method of detecting infection in implanted artificial joints using an implanted LED light and sensor integrated into the implant. The technology of the present invention comprises a recess on the scale of a few millimeters that is disposed in a non-articulating surface of a prosthetic joint, an LED light source, and a photosensor placed in the recess, providing access to the synovial fluid of the joint without compromising prosthetic function. The photosensor is precisely calibrated to detect fine changes in the quality of the fluid flowing through the joint. The presence of an immune response is detected easily by the photosensor. Changes in quality corresponding to an immune response trigger a wireless notification device, alerting the user(s) to the presence of infection at the site of implantation.

Early detection and treatment of periprosthetic infection allows for treatment with a course of antibiotics rather than additional surgery,...
Our invention provides a device for and a method of detecting infection in implanted artificial joints using an implanted LED light and sensor integrated into the implant. The technology of the present invention comprises a recess on the scale of a few millimeters that is disposed in a non-articulating surface of a prosthetic joint, an LED light source, and a photosensor placed in the recess, providing access to the synovial fluid of the joint without compromising prosthetic function. The photosensor is precisely calibrated to detect fine changes in the quality of the fluid flowing through the joint. The presence of an immune response is detected easily by the photosensor. Changes in quality corresponding to an immune response trigger a wireless notification device, alerting the user(s) to the presence of infection at the site of implantation.

Early detection and treatment of periprosthetic infection allows for treatment with a course of antibiotics rather than additional surgery, which is incredibly costly both financially and in quality of life. Patients who receive antibiotic treatment prior to biofilm formation recover from infections >95% of the time. Current methods of detecting infection rely on patients presenting symptoms, which is a sign of advanced infection, and involve blood tests and radiography which are invasive and unreliable. Our device detects infection at the source and is sensitive enough to provide an early warning to the patient before they begin to present symptoms.

Applications of the present invention include detection of infection in artificial joints, detection of infection in arterial stents, detection of infection in ventricular shunts, detection of infection in fracture-fixation devices, detection of infection in implanted pacemaker-defibrillators, and with modifications to provide for embodiments of the present invention, detection and simultaneous suppression of infection in implanted medical devices.
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